A New Approach to RNA Synthesis: Immobilization of Stably and Functionally Co-Tethered Promoter DNA and T7 RNA Polymerase
Kithmie MalagodaPathiranage, Ruptanu Banerjee, and Craig T. Martin, Nucleic Acids Research, July, 2024 Current approaches to RNA synthesis/manufacturing require substantial (and incomplete) purification post-synthesis. We have previously demonstrated the synthesis of RNA from a complex in which T7 RNA polymerase is …