News

October 28, 2021. We’re excited (yet again!) to announce that the lab has been selected for substantial funding from the Wellcome Leap R3 (RNA Readiness+Response) program – “R3 seeks to change the dynamics and costs of biologics development and production, addressing the limitations of current manufacturing by establishing RNA as a versatile, deployable, standardized, multi-product platform technology.” We will be hiring four new postdocs to work on materials, microfluidics, and biochemistry/enzymology. Inquire here to join us!

October 15, 2021. We’re excited to announce that we have received a Manning/IALS Phase II Innovation Award to accelerate our NIH-funded efforts at developing a flow reactor for RNA manufacturing. We’re actively seeking a talented postdoctoral candidate to join us, preferably with experience in microfluidics and/or materials for the immobilization of proteins and/or DNA. Inquiries welcomed.

Welcome two new undergraduate researchers to the lab: Alex Kyranos (B.S. in Biology expected 2022) and Josh Paine (B.S. in Chemistry expected 2023).

July 22, 2021. Congratulations to Elvan and Luis. Their manuscript demonstrating the proof of principle co-tethered transcription system (inspired by Eddie’s earlier pioneering work) was just published in the Journal of Biological Chemistry. Read about it in our publications.

June 25, 2021. Kithmie does it again! First Place Award for Short Talks at the 2021 RNA Therapeutics: From Concept to Clinic Conference.

June 25, 2021. The lab presents two posters and a short talk at the 2021 RNA Therapeutics: From Concept to Clinic Conference. Nice work everyone!

June 11, 2021 – Ruptanu has been selected as an NIH Chemistry-Biology Interface Program Trainee!

May 13-14, 2021 – Congratulations to graduating seniors Amelia (BS, Chemistry) and Julia (BS, Biochemistry & Molecular Biology)! We look forward to hearing back from them frequently.

April 12, 2021 – Congratulations to graduating senior Amelia, who has earned four awards from the Dept of Chemistry: the Mr Tompkins Award, the 2021 Connecticut Valley Section/American Chemical Society Award, the Royal Society of Chemistry Certificate of Excellence for 2021, and a one-year membership to the American Chemical Society. A well-earned set of awards!

November 16, 2020 – While not exactly Martin Lab news, we are extremely excited by the preliminary reports coming from BioNTech/Pfizer and Moderna, suggesting outstanding success in their SARS-CoV-2 (COVID-19) mRNA vaccine development! This is obviously great news globally, but also provides compelling evidence that mRNA therapeutics, more broadly, will have a huge impact across a wide variety of diseases!

November 10, 2020 – Kithmie wins 3rd place (conference-wide) for her poster presentation at the 8th International mRNA Health Conference!

October 7, 2020. We’re so excited to be vicariously enjoying the well-earned successes of Jennifer Doudna and Emmanuelle Charpentier, winners of the 2020 Nobel Prize in Chemistry for their ground breaking work on CRISPR!

August 20, 2020. Elvan Cavaç defended her Ph.D. dissertation, in front of an international Zoom audience. Congratulations to Elvan for some ground-breaking research, very well received. She will be starting a UMass MBA program, as a Business Innovation Fellow, almost immediately!

May 28, 2020. Alum Yasaman Gholamalipour has won the highly competitive HDSA Berman-Topper Family HD Career Development Fellowship to support her in her postdoctoral research that will attempt to reverse the CAG repeat expansion sequence in the mutant huntingtin gene in cellular and animal HD models using the CRISPR-Cas9 nickase genome-editing tool. Congratulations!!

April 1, 2020. Lab receives new four year NIH award “Systems for Dramatically Improved Synthetic RNA”

April 2020. Lab receives a 2020 Acorn Innovation Award from the Massachusetts Technology Transfer Center!

April 10, 2020. Congratulations to Will for being chosen as one of only four “Rising Researchers” across campus! In the Fall, he will start in the Graduate Program in Molecular Microbiology at Tufts University.

November 22, 2019. Elvan presents a talk on her research at the 2019 Life Science Graduate Research Symposium, University of Massachusetts, Amherst.

November 13, 2019. Craig presented a seminar at TriLink Biotechnologies, San Diego, CA.

September 18, 2019. Craig presented a seminar at Arrakis Therapeutics in Waltham, MA.

September 11, 2019. Congratulations to alum Gang Han (PhD 2007, joint w/ Rotello), newly promoted to Full Professor at the University of Massachusetts Medical School. Hear him talk about his successes in bioengineered night vision here.

September 7, 2019. Elvan has been selected as a student speaker at the Annual Retreat of the Program in Molecular & Cellular Biology (MCB).

August 27, 2019. Yasaman, selected as one of four student speakers at the Annual Chemistry Department Posterfest, wins an award for her outstanding talk!

August 27, 2019. Elvan wins an award for her poster presentation at the Annual Chemistry Department Posterfest!

August 16, 2019. Yasaman successfully defended her Ph.D. dissertation!! Great job!

June 26-28, 2019. Yasaman and Kithmie (and Craig) presented a poster at the 2019 RNA Therapeutics Conference: From Mechanism to Therapy, in Worcester, MA. They presented recent work from our lab that offers approaches for better transcription by T7 RNA polymerase.

June 11-16, 2019. Elvan presented a poster at the Annual Meeting of the RNA Society, in Krakow, Poland. Her poster presented two new approaches from our group that offer better (higher yield, higher quality!) RNA synthesis by T7 RNA polymerase.

June 3, 2019. Yasaman presented her recently submitted work at the Pioneer Valley RNA Club (PiVaRC) RNA Salon.

May 30, 2019 – Lab receives Phase I Manning Research Fellow Award.

Feb 21, 2019. Craig presented a seminar at New England Biolabs.

Nov 12-13, 2018. Craig spoke at the 6th International mRNA Health Conference, in Cambridge, MA

Sept 14, 2018. Yasaman’s paper, “3’ end additions by T7 RNA polymerase are RNA self-templated, distributive, and diverse in character – RNA-Seq analyses,” published in Nucl Acids Res, 46, 9253-9263, was selected by the editors as a Breakthrough Article.” Congratulations Yasi!!

June 28-30, 2018. Yasaman presented her work at the inaugural RNA Therapeutics from Base Pairs to Bedsides conference, in Worcester, MA. She had lots of positive queries from the attendees.