Daniel K. Muller, Craig T. Martin, and Joseph E. Coleman, Biochemistry 28, 3306-3313, 1989 The interactions of T7 RNA polymerase with its promoter DNA have been previously probed in footprinting experiments with either DNase I or (methidiumpropyl-EDTA)-Fe(II) to cleave unprotected DNA …

T7 RNA Polymerase Interacts with Its Promoter from One Side of the DNA Helix Read more »

Craig T. Martin and Joseph E. Coleman, Biochemistry 26, 2690-2696, 1987 Specific interactions between T7 RNA polymerase and its promoter have been studied by asimple steady-state kinetic assay using synthetic oligonucleotide promoters that produce a short five-basemessage. A series of …

Kinetic Analysis of T7 RNA Polymerase-Promoter Interactions with Small Synthetic Promoters Read more »

Craig T. Martin, Charles P. Scholes, Sunney I. Chan, Journal of Biological Chemistry 260, 2857-2861, 1985 A histidine auxotroph of Saccharomyces cerevisiae has been used to metabolically incorporate [1,3-15N2] histidine into yeast cytochrome c oxidase. Electron nuclear double resonance (ENDOR) …

The identification of histidine ligands to cytochrome a in cytochrome c oxidase Read more »

Robert R. Birge, Albert F. Lawrence, Thomas M. Cooper, Craig T. Martin, David F. Blair, Sunney I. Chan, Nonlinear Electrodynamics in Biological Systems, 107-120, 1984 The energy stored in the primary photochemical event of light adapted bacteriorhodopsin (~16 kcal mol-1) …

The Energetics and Molecular Dynamics of the Proton Pumping Photocycle in Bacteriorhodopsin Read more »

DF Blair, GW Campbell, V Lum, CT Martin, HB Gray, BG Malmström, Sunney I. Chan, Journal of Inorganic Biochemistry 19, 65-73 Resonance Raman (RR) spectra of Rhus vernicifera laccase and Polyporus versicolor laccase in several perturbed states are reported. Coordination of fluoride to the …

A resonance Raman investigation of perturbed states of tree and fungal laccase Read more »

Craig T. Martin, Randall H. Morse, Robert M. Kanne, Harry B. Gray, Bo G. Malmström, Sunney I. Chan, Biochemistry 20, 5147-5155, 1981 The reactions of nitric oxide (NO) with the oxi- dized and reduced forms of fungal and tree laccase, as well as with tree laccase depleted in type 2 copper, are reported. The products of the reactions were determined by NMR and mass spectroscopy, whereas the oxidation states of the enzymes were monitored by EPR and optical spectroscopy. All three copper sites in fungal lacease are reduced by NO. In addition,NO forms a specific complex with the reduced type 2 copper. NO similarly reduces all of the copper sites in tree lacease, but it also oxidizes the reduced sites produced by ascorbate or NO reduction. A catalytic cycle is set up in which N20, …

Reactions of nitric oxide with tree and fungal laccase Read more »